This book aims to present the insights, innovations, and transformations resulting from interventionist studies in the field of Occupational Health, conducted under the thematic project Innovation and Transformation for Occupational Risk Prevention Activity (Itapar). These studies address the urgent need for practical research that not only improves working conditions but also empowers workers with the skills and knowledge necessary to drive these changes. The formative interventions presented innovatively combine concepts and techniques from Activity Ergonomics with the Change Laboratory (CL) method, aiming for the collaborative development of solutions to overcome contradictions found within and between activity systems.